Investigation into conolidine has brought about discovery of an opioid receptor in your body termed ACKR3/CXCR7. ACKR3 seems to be the most sought after goal for conolidine, which also disregards the other 4 classical opioid receptors(3). There's interest in applying conolidine like a pain-reliever determined by proof from animal https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers